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FC131 TFA (606968-52-9 free base)
CAS No. ——
FC131 TFA (606968-52-9 free base)( —— )
Catalog No. M30047 CAS No. ——
FC131 TFA is a CXCR4 antagonist that inhibits the binding of [125I] -sdf-1 to CXCR4 with an IC50 value of 4.5 nM and has anti-hiv activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 122 | Get Quote |
|
| 5MG | 260 | Get Quote |
|
| 10MG | 437 | Get Quote |
|
| 25MG | 716 | Get Quote |
|
| 50MG | 1017 | Get Quote |
|
| 100MG | 1422 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
Biological Information
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Product NameFC131 TFA (606968-52-9 free base)
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NoteResearch use only, not for human use.
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Brief DescriptionFC131 TFA is a CXCR4 antagonist that inhibits the binding of [125I] -sdf-1 to CXCR4 with an IC50 value of 4.5 nM and has anti-hiv activity.
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DescriptionFC131 TFA is a CXCR4 antagonist that inhibits the binding of [125I] -sdf-1 to CXCR4 with an IC50 value of 4.5 nM and has anti-hiv activity.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAutophagy
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TargetCXCR
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RecptorIC50: 4.5 nM ([125I]-SDF-1-CXCR4)
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Research Area——
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Indication——
Chemical Information
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CAS Number——
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Formula Weight843.85
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Molecular FormulaC38H48F3N11O8
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Purity>98% (HPLC)
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SolubilityDMSO : 250 mg/mL (296.26 mM; Need ultrasonic)
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SMILES——
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Chemical NameSequence:{2-Naph-Ala}-{Gly}-{Tyr}-{Arg}-{Arg}
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
Tamamura H, et al. Stereoselective synthesis of [L-Arg-L/D-3-(2-naphthyl)alanine]-type (E)-alkene dipeptide isosteres and its application to the synthesis and biological evaluation of pseudopeptide analogues of the CXCR4 antagonist FC131. J Med Chem. 2005 Jan 27;48(2):380-91.
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FC131 TFA
FC131 TFA is an antagonist of CXCR4 that inhibits the binding of [125I] -sdf-1 to CXCR4(IC50 : 4.5 nM ), and has anti-hiv activity.
